Nanomedicine & Nanotechnology Open Access (NNOA)

ISSN: 2574-187X

Research Article

Square Wave Voltammetric Determination of Piperazine Using Gold Electrode in Human Biological Samples

Authors: Vijay P Pattar , Nagappa L Teradal and Sharanappa T Nandibewoor*

DOI: 10.23880/nnoa-16000199

Abstract

From voltammetric experiments, the electrochemical behavior of piperazine (PPZ) was determined at gold electrode (GE) in pH 7, 0.2 M phosphate buffer solution. It is shown that in the presence of PPZ the electrochemical oxidation at a GE was irreversible process. Based on the experimental results suitable mechanism was proposed. The electrooxidation of PPZ showed diffusion controlled. Under optimized conditions, linearity between the peak current and PPZ concentration was observed in the range of 1.0x10-6–1.7x10-5 M and LOD was found to be 4.49 x 10-8 M. Further, the sensor was used for the assay of PPZ in biological samples. 

Keywords: Piperazine; Electroanalysis; Gold electrode; Square wave voltammetry

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