Sulindac-Induced Stevens-Johnson Toxic Epidermal Necrolysis Syndrome: Case Report

Authors: Aguilar Silva A*, Espinosa Tavitas M, Carpio Orantes LD, Lopez Cabrera Y, Mayo Martinez ML and Guerrero Martinez MD

DOI: 10.23880/cdoaj-16000220

Volume 5, Issue 4

Abstract

We present the case of a 42-year-old patient who came to the emergency room after taking sulindac as a treatment for diabetic neuropathy, presenting 4 days later a maculo-violaceous rash on the chest accompanied by vesicles, pruritus, extending to the abdomen and upper extremities and lower lesions and fever, affecting approximately 25% of the body surface, basophil degranulation was performed, reporting 50% for sulindac. A literature review was carried out in order to update the current knowledge about Steven Johnson syndrome in the hospital environment, etiology, clinical manifestations, epidemiology, diagnosis and treatment.

Keywords: Sulindac; Steven Johnson syndrome; Toxic epidermal necrolysis

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