Does Diabetes and Hypertension have Common Pathophysiology-A Study

Authors: Premkumar D*, Perumal KK, Pandirangan T, Tamilselvam, Diwakar A and Sawrirajan R

DOI: 10.23880/doij-16000233

Volume 5, Issue 4

Abstract

Diabetes and hypertension often occur together. Hence they may share some common causes. These causes may be obesity, inflammation, oxidative stress and insulin resistance. Type 2 diabetes may cause hypertension by atherosclerosis. It suggests the importance of keeping an optimal glycaemic profile in general populations. BP screening and monitoring, especially systolic BP, is essential in patients with type 2 diabetes. There are many theories and there is no confirmed mechanisms but, genetic predisposition, insulin resistance, inflammation, oxidative stress, endothelial dysfunction, and have been suggested to explain the link between higher hypertension and diabetes. In our study it was found that 51.8 percent had normal blood sugar and 19% are pre diabetic and 29% are diabetic. As the age increases the incidence of prediabetes and diabetes also increases. Incidence of Diabetes is more in males than in females. Similarly, the prediabetes is also more common in males. Among females 10.75% had normal blood sugar and normal BP and among Males only 3.7% had normal blood sugar and normal BP. Females are more in the prediabetes and elevated & Stage I BP and more males are diabetic and hypertensive.

Keywords: Diabetes; Pre-diabetes; Hypertension; Elevated BP; Inflammation; Endothelial Damage; Anti-hypertensives

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