ISSN: 2574-2701
Authors: Simardeep Kaur and Suresh Kumar*
Nutrition, lifestyle, behavior, and other environmental factors affect human health that may control pathogenesis of various diseases, and it is regulated through epigenetic modifications. Nutrition is an indispensable environmental factor that not only impacts our growth and development but also the health by affecting epigenetic phenomena. Furthermore, these changes might impact next generation via transgenerational inheritance of epigenetic alterations; thus, making them important health issues for the society. Certain nutrients and bioactive food components are able to alter epigenetic status at DNA methylation and histone modulation levels, which might modulate expression of the genes associated with patho-physiological processes. In addition to the genetics, health condition of an organism might be affected by the integration of environmental factors/signals acting through epigenetic changes. Therefore, understanding the molecular (epigenetic) basis of environmental factors has become a need of the day towards development of preventative strategies against various pathological conditions like obesity, type II diabetes, cardiovascular diseases, cancer etc. utilizing a personalized dietary chart.
Keywords: Bioactive Food Component; Cancer; Disease; Environment; Epigenetics; Genetics; Nutrient
