In vitro Antioxidant Activity of Trichosanthes dioica Root

Authors: Bhattacharya S* and Haldar PK

Volume 4, Issue 4

Abstract

Trichosanthes dioica Roxb. (Cucurbitaceae), called pointed gourd in English, Potol in Bengali is a dioecious climber vine found wild throughout the plains of India and cultivated widely for its consumable fruits. The objective of the present study is to evaluate the in vitro antioxidant activity of hydroalcohol extract of roots from Trichosanthes dioica Roxb (TDA). In vitro antioxidant activity of TDA was assessed by DPPH, nitric oxide, hydroxyl radical, peroxynitrite and superoxide radical scavenging methods. TDA exhibited marked and concentration dependent free radical scavenging affect in all five in vitro models. The results from the present work demonstrated that T. dioica root possesses promising in vitro antioxidant effect which may provide the basis of its several activities in vivo.

Keywords: Trichosanthes dioica; Antioxidant activity; Free Radical; DPPH; Root

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