Anaesthesia and Critical Care Medicine Journal (ACCMJ)

ISSN: 2577-4301

Research Article

Effect of Alkalinization on the Onset Action of Lignocaine in Epidural Anaesthesia

Authors: Haque MM* and Chandra Sarkar N

DOI: 10.23880/accmj-16000183

Abstract

Lumbar epidural anaesthesia is one among the commonly performed regional anaesthesia especially for lower abdominal, lower limb surgeries and also for post-operative pain relief. Its ability to produce neuraxial blockade without dural puncture is an attractive option for spinal anaesthesia. To study the effect of alkalinization on the onset action of lignocaine in epidural anaesthesia. This study was done in Shaheed Ziaur Rahman Medical College & Hospital, Bogura, Bangladesh in the year of 2018-19. After the institutional ethical committee approval and informed consent from the patient, 100 patients posted for lower abdominal surgery were selected after inclusion and exclusion criteria. The inclusion criteria were ASA I&II of both gender with an age group of 20-60 years and the exclusion criteria were age below 20 years and above 60 years, weight 45 to 85 kgs, spinal deformities, local sepsis, bleeding disorder and patient refusal. After the institutional ethical committee approval and informed consent from the patient, 100 patients posted for lower abdominal surgery were selected after inclusion and exclusion criteria and they were divided into two groups. Group S received Lignocaine with adrenaline added with Saline and Group A received alkalized Lignocaine (with Sodium bicarbonate) with adrenaline. It was concluded that alkalinization shortens the onset of action of Lignocaine.

Keywords: Epidural anaesthesia; Alkalinization; Sodium bicarbonate; Saline; Lignocaine

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