Stress Response in Surgery, Anesthetics Role and Effect on Cognition: A Review

Authors: Agrawal J*, Srivathsan J and Youvraj M

DOI: 10.23880/accmj-16000184

Volume 6, Issue 1

Abstract

The stress response to surgery, critical illness, trauma, and burns is characterized by derangements of metabolic and physiological processes which in turn activate the inflammatory, hormonal (sympathoadrenal), immunological, and genomic responses. The surgery-induced stress response is almost similar to that triggered by traumatic injuries; however the duration of the stress response varies according to the severity of injury. Although the stress response to acute trauma evolved to improve chances of survival following injury, in modern surgical practice the stress response can be detrimental.

Keywords: Cognition; Surgery; Stress Response; Anesthetics Role; Trauma; Hypothalamic-Pituitary-Adrenal Axis

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