Putative Role of Micro-RNAs in Female Reproductive Tract

Authors: Hitit M and Kurar E

DOI: 10.23880/oajvsr-16000131

Volume 2, Issue 2

Abstract

Female reproductive tract is composed of ovarium, oviduct, cervix and uterus. Development and function of reproductive tract is dispensable for maintenance and achievement of reproduction. Reproductive tract responses to cyclic changes and ovarium hormones which provide optimum conditions for gamete movement and development. While the potential influence of pituitary and gonadal hormones on reproductive function is clearly understood, the molecular mechanism regulating reproductive tract remains elusive. Although, post-transcriptional gene regulation has critical role in cell differentiation and proliferation, little information is available in post-transcriptional gene regulation in reproductive tract. Post-transcriptional gene regulation includes splicing, processing, transport and translation of mRNA. In addition, role of RNA binding proteins and recently discovered miRNAs were also implicated in reproductive tract.

Keywords: miRNAs; Reproductive Tract; Gene Expression

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