Tadalafil 5 Mg/Daily in the Treatment of Vision Impairment, A Single Case Study: Optic Nerve and Hsp70 Up-Regulation as a New Medical Hypothesis for Vision Improvement

Authors: Ahed J Alkhatib*

DOI: 10.23880/nnoaj-16000156

Volume 6, Issue 1

Abstract

Introduction: The use of tadalafil (daily 5 mg) has proved efficient in treating depression in patients with erectile dysfunction based on its ability to upregulate the expression of HSP70. We previously showed its efficacy in treating prediabetes, and cerebral palsy. Study objectives: The main objective of the present study is to introduce the efficacy of using tadalafil (5 mg daily) in treating vision impairment as a new medical hypothesis. Methods: A man 56 years with type 2 diabetes and hypertension has suffered from vision impairment since years. He was seeking for non-conventional therapeutic options to restore or reverse vision impairment. The patient was advised to use tadalafil (5 mg/day) for 1 month. Results: Following one month of treatment, the patient reported that his vision impairment was reversed to a high level. Conclusion: The use of tadalafil (5 mg/day) is a novel therapeutic approach for the treatment of vision impairment through possible up-regulation of HSP70.

Keywords: Vision; Impairment; Tadalafil; HSP70; Up-Regulation

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