ISSN: 2574-187X
Evaluation of Antioxidant Properties of Silver Nanoparticle Embedded Medicinal Patch
Nanotechnology is the most promising field for generating new applications in medicine. Nanosilver particles are generally smaller than 100 nm and contain 20–15,000 silver atoms. Silver nanoparticles are known for its antioxidant effects and are gaining importance due to this property. The aim of the current study was to evaluate the antioxidant properties of a nanosilver embedded medicinal patch. Transdermal patches are useful in delivering a controlled amount of drug into the bloodstream through the skin. An attempt has been made here to formulate medicinal transdermal patches by adding chitosan as the flexibility and permeation enhancer, glycerol as plasticizer, gelatin as moisturizer, and silver nanoparticles as the drug. Here, silver nanoparticles were prepared by chemical reduction method. The formation of the silver nanoparticles was confirmed using UV-Vis and FTIR spectrometers. The prepared transdermal patches were then evaluated for antioxidant activity by Reducing Power Assay method. The results showed that the patch had the desirable characteristics and fulfilled the essential requirements for reasonable wound dressing.
Keywords:
Chitosan; Gelatin; Silver nanoparticles; Transdermal patch; Antioxidant activity
