ISSN: 2578-5001
Authors: Muhammed AUA, Afzalul B, Nazrul I*, Mashud P, Kamruzzaman Z and Obaidul H
The wide variation of the spectrum of Glomerulonephritis (GN) is noted worldwide. In Bangladesh, the spectrum and trends of GN cannot be determined definitely due to the absence of central kidney biopsy registry. The aim of this study was to see the spectrum and trends of Glomerulonephritis in our population. All the kidney biopsies were done in Shaheed Sheikh Abu Naser Specialized hospital, Khulna, Bangladesh from 2015 to 2020, and reviewed retrospectively. A total of 151 native kidney biopsies were examined by light and immunofluorescence microscopy. The mean age of the study patients was 31.3 ± 13.79 years with a range of 11-66 years, 52% were male and 48 % were female. Primary glomerulonephritis was observed in 91% of cases and secondary glomerulonephritis was in 9% of cases. Mesensialproliferative glomerulonephritis (36.48%) is on the slight decline in Bangladesh, though it still remains the commonest glomerulonephritis in this study. Membranoproliferative glomerulonephritis (27%) was the second observed GN followed by Membranous nephropathy (11.48%). Minimal change disease was observed very low in number e.g. 2.02%. Lupus Nephritis was the commonest secondary GN. Mesangialproliferative and Membranoproliferative glomerulonephritis were found in high incidence in our population. So it is essential to improve our socioeconomic and hygienic conditions for the prevention of these infection-related glomerulonephritis. This study may be helpful to establish a biopsy registry in this part of the world, which would be opened a platform for future research and planning.
Keywords: Glomerulonephritis; Mesangialproliferative Glomerulonephritis; Renal Biopsy; Histopathology
