Human Papilloma Virus: Emerging Risk Factor in Oral Squamous Cell Carcinoma among Asians

Authors: Medawela RMSHB and Ratnayake DRDL

DOI: 10.23880/oajds-16000132

Volume 2, Issue 2

Abstract

Oral and oro-pharyngeal cancer grouped together is the 6th most common cancer in the world. Annual estimated global incidence is around 300373 for oral cancer (GLOBOCAN 2012). South East Asia region (SEARO) accounting for 1/3rd of total incidence of oral cancer in the world. Globally Oral cancer is seen more commonly in men than in women. The risk of developing oral cancer increases with age and the majority of cases occur in people aged 50 years or over. Additionally, the incidence of Oral squamous cell carcinoma (OSCC) is increasing among young white individuals age 18 to 44 years, particularly among white women. Tongue is the most common site for intra-oral cancer among European and US populations, accounting for 40-50% of oral cancers. In contrast Buccal cancer is more common among Asian populations due to betel quid/tobacco chewing habits. For most countries age-adjusted death rates from oral cancer have been estimated at 3-4 per 100,000 men and 1.5-2.0 per 100,000 for women.

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