Short Term Hospital Outcome of Ischemic Stroke Patient Presenting with Hyponatremia

Authors: Goutam Saha*, Md. Shafiqul Islam, Uttam kumar Das, Md. Rezaul karim Talukder, Sajal Kumar Shill, Jobaidul Alam Bhuiya, Md. Magfur Rahman, Sabia Siddika

DOI: 10.23880/nnoaj-16000161

Volume 6, Issue 1

Abstract

This observational prospective study was performed in the Department of Neurology and Medicine wards at Mymensingh Medical College Hospital, Bangladesh over the period of one year to assess the short term hospital outcome of ischemic stroke patients presenting with hyponatremia. Patients diagnosed as ischaemic stroke were primarily enrolled as study population in this study. Of them 50 patients were selected whose serum sodium was less than 135 meq/L as hyponatremic and another fifty patients were selected whose serum sodium was normal level (135-145) meq/L as normonatremic. The patients were followed up at admission and at the time of discharge. Disability was assessed by the mRS score. Mean age of hyponatremia patients and normonatremia patients were 64.8 ± 12.3 years and 60.9 ± 13.1 years respectively. Male were predominant in both groups. Mean Na+ level in hyponatremia patients was significantly lower than normonatremia patients (127.6 ± 5.7 mg/dl vs 139.3 ± 3.5 mg/dl). Even mortality rate was higher in hyponatremia group (12.0%) than that of normonatremia group (4.0%) the difference was not statistically significant (p>0.05). No significant difference was observed in disability rate between hyponatremia group and normonatremia group (81.8% vs 72.9%). The mean mRS scores at the time of admission (4.16 ± 1.03 vs 3.74 ± 0.75) and at the time of discharge (3.56 ± 1.21 vs 3.04 ± 0.98) were significantly higher in hyponatremia than normonatremia patients. This study result shows that mRS score is higher in hyponatremic stroke patients than that of normonatrimic stroke patients.

Keywords: Ischaemic Stroke; Hyponatremia

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