ISSN: 2639-2038
Authors: Turdieva Sh T and Nasirova GR
Background: To study the effects of bacteriophage therapy on acute tonsillitis in children and adolescents in an outpatient setting. Materials and methods: A total of 128 children aged 3 to 14 years with acute tonsillitis were examined. General clinical characteristics, pharyngoscopy findings, and bacteriological results from a tonsil smear were collected. Bacteriophage therapy was carried out using a liquid complex pyobacteriophage (pyobacteriophage complex liquid - PСL). Results: The main pathogens of acute tonsillitis in children were Staphylococcus aureus and Streptococcus pyogenes (from 24.2% to 42.2%). Bacteriophage therapy was associated with decreases in swelling in the tonsils and general intoxication signs after 2-3 days of treatment. In the blood, the level of leukocytes in 85.07% of the patients returned to normal on the 4th day of the disease. Conclusion: The main predictor of the development of acute tonsillitis in children was viral infection (75.8%), which contributed to increased colonization of the tonsils by pathogenic bacteria, mainly Staphylococcus aureus and Streptococcus pyogenes. The use of bacteriophage therapy for the conservative treatment of acute tonsillitis in children improved their condition 1.4 times faster than standard therapy during the acute period of the disease.
Keywords: Acute Tonsillitis; Children; Tonsils; Bacterium; Bacteriophage
