Mycobacterium Tuberculosis, Culturing and PCR Optimization

Authors: Muhammad Waqar Mazhar , Javaria Mahmood , Hira Aslam , Saira Saif , Iqra Kamal , Masooma Batool Shahzadi , Mudasara Sikandar , Sadaf Javed1 , Hira Tahir , Nibras Waqas and Fatima Mazhar

DOI: 10.23880/aemb-16000108

Volume 3, Issue 1

Abstract

The genus Acinetobacter baumannii has undergone substantial taxonomic modifications over the last 30 years. Acinetobacter baumannii is one of the most important representatives of the genus and pathogen for healthcare facilities globally. Over the last 15 years, its clinical significance shows that it has the ability to acquire resistance against antibiotics in this threatening antibiotic era. Naturally A.baumannii can easily be isolated from different sources throughout whole world, found mostly in water, soil, sputum and many healthcare environments, is a non-fermenting, non-spore forming and gram negative coccobacilli. Pneumonia caused by MDR strains of Acinetobacter baumannii creating serious issues for Physicians to treat it properly. Risk factor for two types of patients recognized to pneumonia infection Acinetobacter baumannii hospital associated pneumonia (AHAP) and Acinetobacter baumannii ventilator associated pneumonia (AVAP), by univariate analysis prior to ceftazidime treatment. It is to be reported that potential risk factors for AVAP includes, imipenem resistance, long duration of hospital stay and fluoroquinolones exposure.

Keywords: Mycobacterium Tuberculosis; Acinetobacter baumannii; Ceftazidime; Fluoroquinolones; Acinetobacter baumannii Ventilator

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