Removal of Oxytetracycline in Pharmaceutical Effluents by Using Synthetic Adsorbents

Authors: Aqsa S , Madiha B , Ayesha and Mohammad N

DOI: 10.23880/nnoa-16000212

Volume 6, Issue 2

Abstract

Simple, accurate, fast, and economical method for removal of OTC in pharma wastewater has been developed. The procedure is based on the adsorption mechanism which leads to the spectrophotometry. Bentone -34 clay is used as an adsorbent for removal of OTC. 0.1 N HCl was used as a mobile phase. The elute was determined spectroscopically, with a Cecil CE 2041 UV/VIS spectrophotometer, in a 1-cm cuvette cell at wavelength range 190−1100 nm, with resolution 0.5 nm. The linear calibration curve was established in the concentration range 0.214-1.070 mg/mL of OTC. From the analyzed data the following results for parameters were obtained linearity correlation R2 > 0.9984), accuracy (Recovery = 91−98 %), sensitivity (LOD = 42.3 mg/mL; LOQ = 48.3 mg/mL), and precision (RSD ≥ 2.0 %) in the respective linear concentration ranges. The method is successfully applied for the removal of OTC as the tested sample improves ICH parameters like accuracy, sensitivity, precision. 

Keywords: Oxytetracycline; Tetracyclines; ICH (International Council of Harmonization)

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