ISSN: 2578-4641
Authors: Kulvinder KK*, Gautam A and Mandeep S
Cancer in addition to the correlated radiotherapy, along with chemotherapy, possesses significant deleterious actions on the male reproductive capacity, resulting in a lot of men infertile. Fertility preservation has become a critical issue with regards to survivors in the last 2 decades, with a lot of professional organizations, have published literature with regards to the guidelines that advocate fertility preservation to assume a routine part of dealing with an man who is supposed to receive cancer treatment. Maximum males possess the capacity of generation of an ejaculate having sufficient semen specimen for fertility preservation by cryopreservation of sperms. Despite different other approaches for collection of sperms are existent certain patients like adult males with azoospermia, besides, prepubertal, boys who do not have the initiation of spermatogenesis, one can’t harvest the sperms, besides all the advances of cryopreservation of testicular tissue cryopreservation, yet translation to adult sperms has not got attained with lot of efforts being directed towards attaining same by particular metabolism manipulation of immature germ cells, besides use of various factors like VEGF &PDGF laden nanoparticles. Thus lot of experimental, besides investigational strategies, give the hope that translation to Clinical scenario that will provide extra pathways In achieving successful fertility preservation.
Keywords: Cancer; Fertility Preservation; Cryopreservation of Sperms; Infertility
