Epidemiology International Journal (EIJ)

ISSN: 2639-2038

Research Article

Adverse Covid-19 Vaccines Reactions in General Medicine: A Clinical-Epidemiological Case Series Reporting of 73 Patients in Toledo’s (Spain) from February to July 2021

Authors: Turabian JL*

DOI: 10.23880/eij-16000204

Abstract

Background: Information on the safety of vaccines against COVID-19 and its dissemination is essential. Objective: To study, in general medicine, clinical-epidemiological characteristics of patients who consulted for self-reported adverse reactions to COVID-19 vaccines. Methodology: An observational, longitudinal and prospective case series study of patients with adverse COVID-19 vaccines reactions (ACVRs) based on a cohort of patients in a family medicine office in Toledo (Spain) was carried out from February 1, 2021 to July 31, 2021. Results: During the 6 months of the study, 73 cases were included. The patients had an average age of 50 years; they were predominantly women, without previous COVID-19, of medium socio-economic level, with 20% ethnic minorities. The majority had a history of chronic diseases, especially endocrinological and Nervous and Senses. The reported symptoms were mostly labelled in the group of symptoms, signs not otherwise specified: Pain injection site, arm pain, fever, chills, dizziness, headache, asthenia, limb paresthesia, lymphadenopathy and edema. 16% were considered definitive and 44% probable. Severity moderate was predominated. Most occurred in the first dose. Conclusion: In the context of general medicine in Toledo (Spain), during the first 6 months of COVID-19 vaccination, no serious adverse effects were found, which were mostly symptoms and signs not otherwise specified, more frequent with the first dose, and affecting to middle-aged women with chronic diseases.

Keywords: COVID-19; Adverse Drug Events; Post-Vaccination Reactions; Vaccine Safety; COVID-19 Vaccine; General Practice; Case Series

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