Prevalence of Some Opportunistic Infections among HIV Positive Women on HAART in Ogun State, Nigeria

Authors: Enitan SS* , Ofurum AG , Abiodun O , Gbise DS , Onoja A , Itodo GE , Olawuyi KA , Agada S , Orsar JS and Odigie JO

DOI: 10.23880/eij-16000206

Volume 5, Issue 4

Abstract

Background: The hallmark of HIV infection is immunosuppression which predisposes to opportunistic infections (OIs), globally; OIs are major cause of morbidity and mortality in people living with HIV (PLWH). This present study examined the prevalence of some opportunistic infections among HIV positive women on HAART in Ogun State. Methods: A total of three hundred (300) blood samples were collected from HIV positive women (≥18years) on HAART attending Babcock University Teaching Hospital (BUTH), Ilishan-Remo, and General Hospital, Ijebu-Ode, Ogun state. Detection of Toxoplasma gondii (TOXO), Rubella virus (RV), Cytomegalovirus (CMV), Herpes Simplex Virus Type-1 and Type-2 (HSV-1 & 2) IgM antibodies in serum sample was carried out using a one-step five in one Bio-System Torch Test Panel Rapid Diagnostic Test (RDT) kit (TOXO, RV, CMV, HSV-1 & HSV-2 Torch IgM Combo Test kit) supplied by Bio systems Inc. Barcelona (Spain) according to the manufacturer instruction. Demographic and clinical information of the subjects were obtained using prepared questionnaires. Raw data were entered in Microsoft excel and statistical analysis was carried out using SPSS Statistics software package (Version 18.0), P-Values

Keywords: HIV; Opportunistic Infections; HAART; Risk Factors; Ogun State; Nigeria

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