Renin Angiotensin System and Covid-19

Authors: Ataie A and Ataee R*

DOI: 10.23880/act-16000224

Volume 6, Issue 4

Abstract

Covid-19 is a new clinical complication in the world and many efforts for its treatment have been done. Renin Angiotensin System (RAS) may have an important role in the control of Covid-19. ACE2 is approved as Covid receptor in lungs and many other organs. Down regulation and up regulation of ACE2 is critical roles in viral infusion into the cells also ACE2 has an important in the level of Angiotensin 2 (ANG2) concentration in the lungs , the high levels of ANG2 may increase inflammation and proliferation and cytokine storms in lung. Angiotensin Receptor Blocker (ARB) such as Losartan may be useful in prophylaxis of lung injury, in this paper we explain about RAS and covid-19 managements in early stages.

Keywords: ACE2; Renin Angiotensin System; Angiotensin Receptor Blocker; Covid-19; ADRS

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