Medical Journal of Clinical Trials & Case Studies (MJCCS)

ISSN: 2578-4838

Research Article

Comparison of Early vs Late Cholecystectomy Performed for Mild Gall Stone Pancreatitis in Terms of Mean Length of Hospital Stay

Authors: Saboor Z, Ahmad S*, Ali H and Shah N

DOI: 10.23880/mjccs-16000303

Abstract

Introduction: Pancreatitis is an inflammatory process in which pancreatic enzymes autodigest the gland. The gland sometimes heals without any impairment of function or any morphologic changes; this process is known as acute pancreatitis. Pancreatitis can also recur intermittently, contributing to the functional and morphologic loss of the gland; recurrent attacks are referred to as chronic pancreatitis. Both forms of pancreatitis may present in the emergency department (ED) with acute clinical findings. Recognizing patients with severe acute pancreatitis as soon as possible is critical for achieving optimal outcomes (see Presentation). Once a working diagnosis of acute pancreatitis is reached, laboratory tests are obtained to support the clinical impression, to help define the etiology, and to look for complications. Diagnostic imaging is unnecessary in most cases but may be obtained when the diagnosis is in doubt, when severe pancreatitis is present, or when a given imaging study might provide specific information needed to answer a clinical question. Image-guided aspiration may be useful. Genetic testing may be considered. Objective: To compare of early vs late cholecystectomy performed for gall stone pancreatitis in terms of mean length of hospital stay Setting: This study was carried out in department of Surgery, Hayatabad Medical Complex, Peshawar. Duration of Study: This study was for 8 months of duration and was carried out after approval of the synopsis. Study Design: Randomized control trial Materials and Methods: This study was conducted in the in the Department of surgery, Hayatabad Medical Complex Peshawar (from 15th September 2014 to 15th May 2015). Through a randomized control Study Design, a total of 60 patients presenting with mild acute pancreatitis were included in the study in a consecutive manner and subjected to early or late cholecystectomy and then the length of hospital stay after the surgery was measured in days. Results: The mean age of the patients of the group 1 was 43.27 years and that of the group 2 was 42.87 years .With regards to gender, there were 22 females and 8 males in group 1 making a percentage of 73.3 and 26.7 respectively. In group 2, 16 patients were females while 14 were males giving a percentage of 53.3 and 46.6 respectively. The mean length of hospital stay for group 1 was 4.63 days and for group 2 was 3.80 days. For females of group 1 the mean length of hospital stay was 4.68 days and for males was 4 days. For the females of group 2, the mean length of hospital stay was 4 days and for males was 3.57 days. Conclusion: Length of hospital stay is longer in early cholecystectomy as compared to late cholecystectomy but is statistically nonsignificant.

Keywords: Acute Pancreatitis; Gall Stones; Cholecystectomy; Emergency Department

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