The Polymorphism in MC1R Gene and Human the Skin Health

Authors: Jiang J, Sun XY, Ren HX, Zhou P and Wang GF*

DOI: 10.23880/izab-16000343

Volume 4, Issue 6

Abstract

The human melanocortin receptor 1(MC1R) gene has a complex structure; it possesses rich polymorphism and variable spliceosome and participates in several key biological pathways. This paper reviews the structure and function of the human MC1R gene and its polymorphisms on the increased risk of cutaneous carcinoma, nevus, Parkinson's disease, vitiligo, and other diseases to provide a theoretical basis for incorporating the MC1R gene into the risk prediction model of human-related diseases.

Keywords: MC1R Gene; Polymorphisms; Skin Disease

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