Open Access Journal of Cancer & Oncology (OAJCO)
ISSN: 2578-4625
Research Article
Prevelance of Ovarian Cancer and its Correlation with Age in
Pakistan
Authors:
Muhammad Waqar Mazhar
,
Saira Saif
,
Asma Taj
,
Sohail Waris
,
Abdul Manan
,
Muhammad Irfan
,
Ahmad Raza
,
Fatima Mazhar
and
Hira Tahir
DOI:
10.23880/oajco-16000177
Abstract
Introduction: Group of diseases that is originated from the different parts of ovaries and cause production of abnormal cells that divide uncontrolled themselves in the ovaries is known as ovarian cancer. OC is mainly classified into majorly three types on the base of three components of ovaries known as epithelium, stroma and germinal cells. Approximately, 7000 women develop OC and 4200 of them die every year in UK. In Pakistan the incidence of OC is increasing at the rate of around 13.6%. Approximately 70% cases are diagnosed at later stages.
Methodology: The blood sample was collected by Layyah region. The CA125 identification through Elisa technique for their better identification on the basis of antibodies. Normal values of CA125 were considered less than 35 U/ml. the other tumor marker was also measured such as fibrinogen, prolactin, CA15.3, PT, APTT, INR, D Dimer, and CA19.9.
Results: The mean age of patients was 59.0 ± 8.1while the minimum and maximum age at which the tumor marker detection was 22 and 74 years. The no of patient was found in order of 25 >24 > 10 in 1st, 2nd and 3rd age groups, respectively. The clinical histopathological test in the ovarian cancer patients show that the tumor size 5.21 ± 3.42, fibrinogen 5.09 ± 1.29, CA199 (U/mL) 121.17 ± 59.76, and D-dimer 0.61 ± 0.31. The CA-125 level increase in ovarian cancer patients it indication as a tumor marker.
Keywords: Ovarian Cancer; CA-125; Transvaginal Ultrasound, Prolactin Level; CA19.9
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