Adipose Derived Mesenchymal Stem Cells Origin, Characteristics and Promises

Authors: Abu-Shahba N*

DOI: 10.23880/jes-16000161

Volume 6, Issue 1

Abstract

Stem cell biology is currently one of the most leading areas of biomedical research, as enthusiasm for their application toward regenerative medicine continues to expand. Mesenchymal stem cells (MSCs), a well characterized population of fibroblastlike cells, exist in almost all tissues and represent a key cell source for tissue repair and regeneration. Adipose tissue derived mesenchymal stem cells (AT-MSCs) represent one of the most promising and advantageous populations of mesenchymal stem cells for use in cell-based therapy and tissue engineering. In the current mini-review we present the origin of AT-MSCs, their general and functional characteristics, and AT-MSCs-based preclinical and clinical approaches.

Keywords: Immuno modulatory; Immuno suppressor; Adipokines; Chemokines; Homeostasis

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