Induction of Neutralizing Immunity against SARS-CoV-2 Omicron Variant by COVID-19 Vaccine Boosters

Authors: Cheepsattayakorn A* , Cheepsattayakorn R and Siriwanarangsun P

DOI: 10.23880/mjccs-16000311

Volume 6, Issue 2

Abstract

The Omicron variant (BA.1/B.1.1.529) is characterized by mutation of an unusually high number, with 26 to 32 changes (up to 36 mutations) in the spike (S) glycoprotein, the key epitopes (target) of neutralizing antibodies. A recent study revealed that the Omicron variant is more likely to cause reinfection than previous SARS-CoV-2 variants, indicating some immune-escape levels.

Keywords:

View PDF