ISSN: 2578-5095
Authors: Dotta P*
Prader-Willi Syndrome (PWS) is a complex multisystemic disorder characterized by several clinical manifestations, including intellectual deficiency, infant lethargy and hypotonia, and subsequent motor development impairment. The purpose of the review was to perform a brief review of literature on the genetic, neuropsychological and psychiatric aspects in Prader-Willi Syndrome. The present study is a review of exploratory literature in the online databases: LILACS, PubMed and Scielo. Patients with SPW predominantly have neuropsychological and psychological comorbidities associated with the syndrome. However, in Brazilian reality, studies focus on genetic aspects and management of problems associated with obesity. Psychological, neuropsychological and behavioral problems come second without proper intervention. The development of researches in Brazilian reality about neuropsychological and psychological aspects of such patients is suggested.
Keywords: Prader-Willi Syndrome; Obesity; Hypotonia; Neuropsychological Function; Bipolar Disorder