Advances in Pharmacology & Clinical Trials (APCT)

ISSN: 2474-9214

Research Article

Prevalence of Antibiotic Resistant Bacteria in Urine Culture from Two Medical Laboratories in Benghazi

Authors: Huda G*

DOI: 10.23880/apct-16000196

Abstract

Background: Urinary tract infection is the most common bacterial infection and is the second after respiratory tract infection in antibiotic prescription. The treatment of UTI is becoming difficult because of the increasing drug resistance against the common bacteria associated with UTI. Objective: This study aimed to determine the bacteria, and their antimicrobial drug resistance, associated with UTI in the Libyan population in the city of Benghazi. Materials and Methods: We performed a retrospective analysis of data of urine culture (2019 -2020) taken from two Medical Laboratories in Benghazi. A total of 1031 urine samples; 318 male, 713 females were analyzed. Result: In this study, Escherichia coli was the most prevalent bacterial uropathogen with (59.84%), followed by Klebsiella pneumoniae (11.58%) and pseudomonas aeruginosa (10%). Then, Proteus and streptococcus pneumoniae had the same prevalence value (3.86%), Enterococcus faecalis (2.7%), and Staphylococcus aureus (2.3%). Neisseria gonorrhea had the lowest (.038). Furthermore, E coli is highly resistance to imipenem, nalidixic acid and nitrofurantoin, and Klebsiella pneumoniae is highly resistance to, imipenem, nitrofurantoin, levofloxacin and ciprofloxacin, pseudomonas is resistance to imipenem, levofloxacin, and ciprofloxacin, proteus mirabilis is resistance to nitrofurantoin, Augmentin and gentamicin. Antibiotics purchasing without prescriptions remains a major problem in Libya. Based on these findings, we recommend appropriate initiatives to monitor and control the use of antibiotics.

Keywords: Urinary Tract Infection; Escherichia coli; Antimicrobial Drug Resistance

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