Major Protein Complexes in Mitochondria-Associated Endoplasmic Reticulum Membranes

Authors: Chonghao Ji, Zhanwei Zhang and Dongjiao Zhang*

DOI: 10.23880/oajds-16000334

Volume 7, Issue 2

Abstract

Mitochondria-associated membranes (MAMs) are structural and functional connection sites between the endoplasmic reticulum (ER) and mitochondria dynamically connected by many molecules. The MAMs mainly rely on these molecules for their various functions, and protein complexes are the most important ones. Here, we focus on the intrinsic protein complexes involved in MAMs of mammalians. Additionally, we summarized some critical information that may be useful for future research.

Keywords: Mitochondria-associated endoplasmic reticulum membranes (MAMs); IP3R-Grp75-VDAC; VAPB-PTPIP51; BAP31-TOM40; Protein Complex

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