Epidermolysis Bullosa. A Rare Disturbance in Clinical Veterinary of Felines

Authors: Errante PR*

DOI: 10.23880/izab-16000379

Volume 5, Issue 3

Abstract

Epidermolysis bullosa is an inherited group of rare genetic dermatosis characterized by mucocutaneous fragility and blister formation, inducible by often minimal trauma. Epidermolysis bullosa is described in humans and domestic animals, and this dermatosis in humans is classified in four categories based predominantly on the plane of skin cleavage in simplex epidermolysis bullosa, junctional epidermolysis bullosa, dystrophic epidermolysis bullosa and Kindler epidermolysis bullosa. In veterinary medicine the classification of epidermolysis bullosa is based in the human classification the according with the level of ultrastructural separation of skin. The epidermolysis bullosa in cats is a rare disease with a description of isolated cases involving the forms simplex, junctional and dystrophic. The laboratory diagnosis of cats under suspicion of epidermolysis bullosa should include dermo histopathology, transmission electron microscopy, immunofluorescence for antigen mapping and when possible, mutation analysis. There is no specific treatment for epidermolysis bullosa in cats, and care is palliative. The few case reports of epidermolysis bullosa in cats indicates a short time of survival with few months to years, being the cats sacrificed or dying during the first months of life. Due to these factors, it is essential the deep studies of disease in cats so that they can present an increase in expectancy and quality of life.

Keywords: Junctional Epidermolysis Bullosa; Mechano-Bullous Dermatosis; Skin; Cats

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