ISSN: 2642-6145
Authors: Jagtap SV*, Jagtap SS, Tuli S and Shah P
Mixed Ductal-Lobular carcinomas (MDLs) show both ductal and lobular morphology. These are rare subtype of invasive breast cancer. We are reporting a 50 year female patient presented to surgical unit having complaint of lump in right breast which was gradually increasing in size. On clinical examination upper inner quadrant of right breast showed a single large lump measuring 4 x 3 x 2.5 cm, firm, tender and fixed posteriorly to chest wall. On sonomammography showed an ill-defined predominantly hypoechoic non circumscribed lesion measuring 8.1 x 2.5 X 2.2 cm with macro and microlobulations reported as BIRADS V highly suggestive of malignancy right breast mass. On histopathology we reported as Invasive breast carcinoma (30%) with invasive lobular carcinoma (60%) and focal neuroendocrine differentiation<10% (RB score = 2+3+2=7) Grade II. On immunohistochemistry tumor was ER, PR positive, and Her2 negative. We are presenting this mixed invasive ductal– lobular carcinomas case for its rarity with clinical, imaging, histomorphological and immunohistochemistry features.
Keywords: Histopathology; Mixed Ductal-Lobular Carcinoma; Breast Cancer; Rare Breast Tumors
