ISSN: 2639-2038
Authors: Filipe BS, Luan SC, Juliana SPS and Matheus DGC*
With the serious advent of the COVID-19 pandemic and the lack of an effective antiviral therapy, the development of vaccines has become the arsenal of first choice, however the urgency of developing these on an emergency basis has raised questions about their effectiveness. The present study aimed to evaluate the possibility of the occurrence of positive serological tests for IgG against S and N proteins, in individuals who have completed at least one month after the third dose of the vaccination schedule available in Brazil, involving four different brands of vaccines, and as well as to verify the real protection capacity against COVID-19 infection. It was possible to observe an absence of patients who tested positive after undergoing immunization with the vaccine regimens involving at least one of the three doses with Janssen vaccine, allowing inferring that this immunogen possibly induces an highly efficient immune response. Through the results obtained, it was also possible to observe that all vaccine protocols that were applied to the research participants proved to be efficient and satisfactory, because, although some patients were infected, there was production of anti-IgG-S antibodies by all of them and all vaccine protocols were 100% effective in protecting research participants from hospitalizations and deaths.
Keywords: COVID-19; Vaccination; Efficacy; Humoral Immunity; IgG Antibodies
