ISSN: 2642-116X
Authors: Aziz FZ, Mahmoud ES* and Al Nabawy RM
Telocytes are a kind of interstitial cell found in a variety of organs, including the uterus. They regulate uterine contractions, maintain pregnancy, and prevent premature labour. The purpose of this research was to look at the organisation and distribution of telocytes in different uterine layers in adult and senile rats at various stages of reproduction. Materials & Methods: Twenty-four female rats were evenly divided between four groups: GI: adult non-pregnant, GII pregnant, GIII postpartum, and GIV senile. The uterine samples from middle one-third of the right horns were processed for light microscopic examination were treated using C-kit stains for immunohistochemical detection of telocytes, and TEM examination. Results: Telocytes were discovered in the endometrium and myometrium of adult non-pregnant uteri as tiny cells with numerous lengthy telopodes. Endometrial telocytes increased significantly, but myometrial telocytes decreased significantly in (GII). (GIII) and (GIV) had the largest count of myometrial telocytes. Conclusion: Telocytes were found in the endometrium and myometrium of the rat uterus. Telocytes serve as a uterine peacekeeper, initiating and coordinating myometrial contraction.
Keywords: Telocytes; Uterus; Rats; Immunohistochemical; Electron Microscope
