ISSN: 2476-2490
Authors: Arellano Barcenas A*
Nasosinusal polyposis is a chronic inflammatory disease that affects the mucosa of the nose and paranasal sinuses, leading to the formation of polyps. The pathophysiology of the disease originates in the ethmoid, where dysbiosis and dysregulation have been evidenced of the immune response in patients diagnosed with sinonasal polyposis. These are made up of loose connective tissue, edema, inflammatory cells, glands, capillaries, and are covered by an epithelium, in most cases, respiratory pseudostratified with ciliated, goblet cells and show an infiltrate of predominantly eosinophils, in addition to neutrophils. mast cells, plasma cells, lymphocytes, monocytes and fibroblasts, adding the presence of IL-5 as the predominant cytosine
Keywords:
