Current Concepts and Future Perspectives of Stem Cell Therapy in Peripheral Arterial Disease

Authors: Kereena Chukka*, Gnaneswar Atturu, Ashok Reddy Somu, Prem Chand Gupta

DOI: 10.23880/jes-16000163

Volume 6, Issue 2

Abstract

Some advanced stage peripheral arterial disease (PAD) patients will not eligible for revascularization strategies. From the last two decades stem cell therapy (SCT) has been explored as an alternative therapy for no option advanced stage PAD patients. Therapeutic motif of this novel therapy is to promote the collateral vessel formation that will improve the blood flow to ischemic leg that in turn can prevent major amputations. This mini review provides the brief outline of the use of autologous and allogeneic SCT for the treatment of advanced stage PAD.

Keywords: Stem Cell Therapy, Peripheral Arterial Disease, Regenerative Medicine, Critical Limb Ischemia (CLI), Autologous, Allogeneic

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