Clinical Pathology & Research Journal (CPRJ)

ISSN: 2642-6145

Review Article

Clinicopathological Characteristics of Testicular Tumors

Authors: Sumat K, Rumana MH* and Parveen Shah

DOI: 10.23880/cprj-16000106

Abstract

Testicular tumors constitute one of the most common tumors of men. Of all the testicular tumors, Germ cell tumors (GCT’s) comprise 95%. Others include sex-cord stromal tumors, mixed germ cell sex-cord stromal tumors, hematopoietic tumors, miscellaneous tumors and secondary tumors. A number of pre-existing medical conditions have been associated with the development of TGCT (testicular germ cell tumour). Most patients of testicular neoplasms present with progressive painless enlargement of testis, history of trauma and hydrocele. Testicular ultrasonography is used to determine the location of a palpable mass when testicular cancer is suspected. Generally, palpable extra-testicular lesions are benign. On the other hand, intratesticular masses, especially if they are palpable, are likely to be malignant and must be surgically explored. The vast majorities of testicular tumors are of germ cell origin and, like the totipotent germ cells from which they arise, may differentiate along several pathways.

Keywords: Testicular Tumor; GCNIS (germ cell neoplasia in situ) Seminoma; Non Seminomatous Germ Cell Tumor; Cryptorchidism; Serum Markers

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