New Experimental Model of Heterotopic Spleen Auto Transplantation

Authors: Khakimov MSh*, Matrizaev TZh, Zhumanazarov AU and Lyubentsova OV

DOI: 10.23880/jqhe-16000304

Volume 5, Issue 6

Abstract

The aim of the study was to develop a new experimental model of heterotopic autotransplantation of the spleen by implanting splenic fragments into subcutaneous fat. Research Material: Experimental studies were conducted on 8 white mongrel rats weighing 300-400 grams at the age of 3 to 4 months. Research Results: Splenectomy is accompanied by significant violations of hemostasis and the immune system of the body, which justifies the feasibility of performing heterotopic autotransplantation of the spleen (GATS). In cases of infection or necrosis of the implant when performing traditional GATS methods, repeated surgical intervention under general anesthesia by laparotomy is required. The developed new method of GATS, which consists in implanting fragments of the spleen into subcutaneous adipose tissue, enveloped by an omentum "on the leg", in cases of necrosis or infection of the allograft, allows you to limit yourself to minimal surgical intervention under local anesthesia.

Keywords: Splenectomy; Auto-transplantation of the Spleen

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