ISSN: 2578-4625
Authors: Sadwal S, Kaur S* and Aniqa A
Breast cancer is the most prevalent disease among women and a challenge for the scientific and medical community. Existing treatments for breast cancer are surgery, radiation, chemotherapy, hormone therapy, and targeted therapy. These treatments have the potential to stop the growth and spread of cancer, particularly when the condition is diagnosed at an early stage. As cancer cells reproduce more frequently than the vast majority of normal cells, chemotherapy has a greater chance of successfully killing cancer cells. Certain pharmaceuticals are able to terminate dividing cells by inflicting damage on the section of the cell’s control centre that is responsible for the process of cell division. Other medications are capable of interfering with the chemical processes that are necessary for cell division. On the other hand, as cancer is often diagnosed at an advanced stage, in which, the process of curing the disease is extremely difficult. Therefore, it is prudent to prevent the occurrence of this deadly disease. Several researches have consistently found an inverse relationship between cancer and natural sources, including plant extracts, fractions and active components. The synergistic and cumulative effects of bioactive phytochemicals found in whole plant extracts have been related to these positive effects. In this review, we attempted to scrutinize the antibreast cancer potential of quite a few extracts/ fractions/active components derived from various plant sources such Alpina galaga, Annona muricata, Ficus carica, Murraya koenigii, Nigella sativa, Rosmarinus officinalis, Urtica dioica, According to recent research, above mention plants have showed anticancer properties by inhibiting cell proliferation, induces apoptosis and causing cell-cycle arrest in preclinical in vitro and in vivo breast cancer models. This review will help the scientific and medical community for novel drug discovery against breast carcinogenesis.
Keywords: Breast Cancer; Medicinal Plants; Plant Extracts; Alpinia Galangal; Annona Muricata; Ficus Carica; Murraya Koenigii; Nigella Sativa; Rosmarinus Officinalis; Urtica Dioica; Phytochemicals
