Practical Considerations in the Design of Antivirals

Authors: Navarro Venegas C* and Antonieta Jara Osorio M

DOI: 10.23880/izab-16000430

Volume 6, Issue 1

Abstract

There is evidence that viruses have been around for many years. Much is even known about their biology, their structural and physicochemical characteristics, but how to combat them through an appropriate design of antivirals is a pending challenge. Although the comparison with antimicrobials is tedious, it should be mentioned that an antimicrobial is designed or has as its target mechanism of action some bacterial structure that does not exist in viruses. Therefore, the design of an antiviral involves knowing the structure and the viral cycle of a particular virus. Today, this issue takes on an important role that has been relegated to a rearguard position due to the existence of vaccines against SARS-CoV-2 viruses and in the case of monkeypox, it should become important even though human smallpox has been eradicated of the planet, according to the WHO, at the beginning of 1980.

Keywords: Antivirals; Viral Structure; Design; Considerations

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