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Treatment of Critical, Severe and Non-Severe COVID-19 by Corticosteroids

Glucocorticoids or corticosteroids have main anti-inflammatory effects to inhibit a vast number of pro-inflammatory genes that involve encoding of cell adhesion molecules, chemokin…

Acute Respiratory Syndrome and Pneumonia caused by COVID-19: A Systematic Review and Meta-Analysis

Objectives: The objectives of this study are to identify sources of the transmission, the starting date of outbreak, epidemic trend of the COVID-19 in China, risk of global spread…

Alpha-1 Antitrypsin Genotypes in Patients with Chronic Obstructive Pulmonary Disease

Alpha-1 antitrypsin (AAT), a proteinase inhibitor produced by the SERPINA1 gene that protects the pulmonary alveoli and other connective tissues in the lungs against the destruc…

Open Lung Approach in Acute Respiratory Distress Syndrome

Outcome of acuten respiratory distress syndrome (ARDS) is conclusively affected by the approach to ventilator support. Substantial controversy in the application of positive end…

Pulmonary Arterial Hypertension Associated Systemic Sclerosis

Pulmonary hypertension (PAH) affects up to 12 % of patients with systemic sclerosis (SSc), with mortality rate of 50 % within 3 years. Patients with SSc-associated PAH (SSc-PAH)…