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"Okutani S"
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Comparative Investigation of In Vitro Induction of DNA Damage
and Micronuclei by Pro-Mutagens in Human-Derived Hepatoma
HepG2 Cells
It is important to know whether the DNA initial lesions are repaired or derive into chromosome aberration, gene mutation and/or cell death to discuss chemical carcinogenicity. To k…
HepG2 Cells
Comet Assay
Micronuclei
Comparative Investigation of In Vitro Genotoxicity of Pro-Mutagens Using Human-Derived Hepatoma HepG2 Cells with Human and Rat Liver S9
The genotoxicity of pro-mutagens has been traditionally detected by test procedures with metabolically incompetent cells requiring addition of exogenous activation mixtures, such a…
HepG2 Cells
Human Liver S9
Rat Liver S9