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Annals of Experimental and Molecular Biology Research Article 4 min read

Correlation of HIV with Prostitution in Punjab

Mazhar MW*
* Corresponding author
ISSN: 2689-8039  10.23880/aemb-16000109  Received: September 24, 2021  Published: October 12, 2021
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Keywords
HIV AIDS Retroviridae Orthoretrovirinae Serology Test
Abstract

HIV belongs to the genus lentivirus within the family of retroviridae and subfamily orthoretrovirinae. In 2017, 1.8 million People were infected with AIDS, and 940,000 died due to this serious disease. HIV found in semen, blood, vaginal and anal fluids, breast milk. it is mainly passes on through unprotected sex, sharing needles or syringes and pregnancy during birth and also passed from one person to other person through this route. The HIV patient’s blood sample collected in vial, serological test and HIV Elisa test performed on Elisa plate Reader. The results shows that 35 (70.00%) out of 50 patients were HIV Elisa positive while 15 individuals were HIV Elisa negative. The maximum no of patients were observed in age 45 and 55, minimum no. of patients were found in both age 63 and 25. These positive tests suggests that the spread of the HIV is due to the unsafe sex or oral sex. Sex may be randomly with HIV affected patients or they do sex without the use of condom. Other main reasons that is responsible for the transmission of HIV includes common use of syringes either by the doctors or by the drug addicted patients that usually share common syringes.

Introduction

HIV one of the most serious health problem of our time. In 2017 1.8 million people were infected with AIDS, and 940,000 died due to this serious disease [1]. HIV belongs to the genus lentivirus within the family of retroviridae and subfamily orthoretrovirinae [2]. HIV mainly affects the white blood cells and causes the lysis of white blood cells. The lysis of cells reduces the immune components of the cells due to this the immune system become weak so the disease provoked by the attack of HIV virus is known as the AIDS (acquired immune deficiency syndrome) [3]. In this disease the immune system of the human become hence it becomes sensitive for the other diseases. AIDS is sexually transmitted disease and also increases by prostitution. The HIV is enveloped virus having glycoproteins as antigens. Majorly, there are two main glycoproteins known as GP120 and GP41 that are involved in the attachment of the HIV virus. Other main feature of the HIV virus is that it contains reverse transcriptase enzymes that do reverse transcription of the m RNA into Cdna [4].

HIV found in semen, blood, vaginal and anal fluids, breast milk, it is mainly passes on through unprotected sex (without a condom), sharing needles or syringes and pregnancy during birth [5]. The HIV patient’s shows symptoms, fever, ash, sore throat, swollen glands, muscle pain, joint aches, headache, upset stomach and body pain. In the early stages of HIV infection the amount of HIV virus in your blood is high and it is more likely to pass the virus onto others [6].

Materials and Methods

The blood sample was collected by Ahmad Pur East region. There were totally 50 patients that belong to different areas of Ahmad Pur East region. The blood sample was put into gel vials and the vials were centrifuged at 3000rpm for ten minutes. After that serum was extracted from all the collected blood samples individually. After that HIV serology test was performed for their initial diagnosis. Serology Test

10ul serum was dropped into the HIV serology kit and one drop of the buffer was also added. Keep for 2 minutes at room temperature. After this thin layer of chromatography runs and show positive and negative cases. The HIV positive samples undergo Elisa technique for their better identification on the basis of antibodies. The Elisa technique has cut value for HIV was 1.0 and show positive cases.

Results

The blood sample of 50 patients belong to different areas of southern Punjab were used in HIV test. The mean age of patients was 45.5 ± 8.1 in Table 1.

Sr. NoPatient DataPatient Age
1Minimum age26
2Maximum Age65
Mean ± S.E45.5 ± 8.1

Table 2: Minimum and maximum age of AIDS patient collected from different areas of southern Punjab.

The age was categorized into 3 groups, 20-40, 41-60 and above 61 age formed 1st, 2nd and 3rd group. Number of patients in age groups, 20-40, 41-60 and above 61 were, 13, 29, and 8 respectively. The no of patient was found in order of 29 >13 > 08 in 2nd, 1st, and 3rd age groups, respectively. The highest no of HIV patient (29) were found in 2nd group while the lowest patients (08) were found in 3rd group. The 8 (61.53%) patients showed the positive Elisa while 5 patients (38.46%) showed no negative Elisa were belong to the1st age group. The 21 (72.41%) patients showed Positive Elisa while 08 patients (27.58%) showed negative Elisa was belong to the 2nd age group. The 6 (75.0%) patients showed positive Elisa while 2 patients (25%) showed negative Elisa was belongs to the 3rd age group. The 35 (70.0%) out of 50 patients were HIV Elisa positive while 15 individuals were HIV Elisa negative (Table 2).

The highest no of AIDS patient (29) were found in 2nd group while the lowest patients (08) were found in 3rd group.

AgePercentage (%)
20-40(n=13)
HIV Positive ELISA08 (61.53%)
HIV Negative ELISA
05 (38.46%)
41-60(n=29)
HIV Positive ELISA21 (72.41%)
HIV Negative ELISA08 (27.58%)
61< (above 61)(n=8)
HIV Positive ELISA06 (75.00%)
HIV Negative ELISA02 (25.00%)

Table 1: Distribution of AIDS patient by age group.

The maximum no of patients were observed in age 45 and 55, minimum no. of patients were found in both age 63 and 25. The results of paired t test was showed that the signification (P<0.05) (0.02) correlation was observed in age group.

Discussion

The peoples of different areas of prostitution were recorded positive for the HIV. These positive tests suggest that the spread of the HIV is due to the unsafe sex or oral sex. This sex may be randomly with HIV affected patients or they do sex without the use of condom. Other main reasons that is responsible for the transmission of HIV includes common use of syringes either by the doctors or by the drug addicted patients that usually share common syringes

Funding

No funds

Conflict of Interest

The authors have no conflict of interest.

References

  1. Seruyange E (2018) Seroepidemiology of vaccine- preventable and emerging RNA viruses in Rwanda.
  2. Mozhi PK, Ganapathy D (2021) Awareness of Structural Biology of HIV among Dental Students. European Journal of Molecular & Clinical Medicine 8(1): 491-503.
  3. Walker EM, Walker SM (2000) Effects of iron overload on the immune system. Ann Clin Lab Sci 30(4): 354-365.
  4. Bowder DM (2018) Contributions of the gp120 Variable Loops to Envelope Glycoprotein Trimer Stability in Primate Lentiviruses. The University of Nebraska- Lincoln.
  5. Kapila A, Chaudhary S, Sharma RB, Vashist H, Gupta A, et al. (2016) A Review on: HIV AIDS. Indian Journal of Pharmaceutical and Biological Research 4(3): 69-73.
  6. Banks Gsss, Gray S (2020) HIV (Human Immunodeficiency Virus) Infection. Health 205: 2802.

Cite this article

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@article{mazhar2021,
  title   = {Correlation of HIV with Prostitution in Punjab},
  author  = {Mazhar MW},
  journal = {Annals of Experimental and Molecular Biology},
  year    = {2021},
  volume  = {3},
  number  = {1},
  doi     = {10.23880/aemb-16000109}
}
Mazhar MW (2021). Correlation of HIV with Prostitution in Punjab. Annals of Experimental and Molecular Biology, 3(1). https://doi.org/10.23880/aemb-16000109
TY  - JOUR
TI  - Correlation of HIV with Prostitution in Punjab
AU  - Mazhar MW
JO  - Annals of Experimental and Molecular Biology
PY  - 2021
VL  - 3
IS  - 1
DO  - 10.23880/aemb-16000109
ER  -