ISSN: 2574-7770
Diagnosis and Prevalence of Sarcopenic Obesity Associated with Low Cardiorespiratory Fitness and Insulin Resistance in Adults Clinically Selected for Lifestyle Modification Program
Authors:
Manda RM1,2, Moreto F1,2,Teixeira O1,2, Torezan GA1 and Burini RC1
Obesity and sarcopenia are anthropometric risk factors that presently, when combined, represent a worse perspective for disability and mortality. The present study aimed to characterize obesity and sarcopenia, as well sarcopenic obesity and its related morbidities in free-living adults clinically selected for a lifestyle modification program(MEV).The study analyzed retrospectively baseline data from 523 individuals, from both genders that spontaneously joint the MEV (Move for Health - "Mexa-se Pró-Saúde")program. The selected sample had data of medical anamneses, anthropometry, physical (and cardiorespiratory) fitness and blood biochemistry. Metabolic Syndrome (MetS) was defined by NCEP-ATP III (2004) criteria and altered waist circumference used for abdominal-obesity definition. Sarcopenia was defined by the lower quartile of muscle-mass index. Statistical analyzes were performed by SAS software 9.2 (p <0.05). The sample was 54.74 ± 10.18 years old, 72.7% females. When compared with non-obese, the abdominal obese subjects presented, as expected, higher BMI, % BF and MMI, along with higher values of triglycerides, blood glucose, HOMA-IR, CRP, uric acid and reduced values of plasma HDL-c, trunk flexibility and VO2max. On the other hand, sarcopenic status (lower MMI quartile)) was associated with lower values of hand grip strength, HDL-c and higher HOMA-IR. The individuals with combined sarcopenic-obesity (20.6%) were older and presented lower muscle strength and aerobic fitness as well lower plasma HDL-c and higher HOMA-IR. However, the presence of MetS was similar in the presence (23.3%) or absence (21.1%) of sarcopenic obesity. Cardiorespiratory fitness was the only age-dependent discriminate of (abdominal) obese sarcopenia. Thus, sarcopenic obesity did not discriminate MetS and was related to lower physical fitness having cardiorespiratory fitness as its is major aging-dependent discriminant.
Keywords:
Sarcopenia; Obesity; Sarcopenic Obesity; Cardiorespiratory Fitness
