Nanomedicine & Nanotechnology Open Access (NNOA)

ISSN: 2574-187X

Editorial

Toxicity of the Quatro Stimuli Nanocontainers in Rats

Authors: Kordas G*

DOI: 10.23880/nnoa-16000243

Abstract

An artificial intelligent drug delivery system (DDS) was produced for cancer treatment, consisting of a shell made of three polymers: the first is sensitive to temperature, the second is sensitive to pH, and the third is sensitive to redox [1]. This innovative DDS called Nano4XX (XX=Dox, Cis) platform was tested on animals, although they were shown to have the potential to cure cancer, as shown in Figure 1 A [2]. When nanocontainers loaded with doxorubicin enter the mice, there is no cure; primary cancer increases with time. The opposite happens when the Nano4Dox platform is enriched with target molecules that detect cancer and are encapsulated in the cancer cell, so they are absorbed and destroyed within the tumor to release the doxorubicin for treatment. In this series of experiments, hyperthermia was applied, and treatment was further improved (Figure 1 B) [1,2].

Keywords: Nanocontainer; Cancer; Drug Delivery; Doxorubicin

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