Development and Characterization of Enteric Coated Diclofenac Sodium Tablet

Authors: Jitendra S, Jatin Kumar S, Bhumika S, Harish S and Gyanesh Kumar S*

DOI: 10.23880/ipcm-16000246

Volume 7, Issue 2

Abstract

Tablets of the drug diclofenac sodium with an enteric coating are used to treat fever, discomfort, and inflammation. The pills are made to withstand the stomach’s acidic environment while dissolving in the small intestine’s alkaline environment. With this delayed release formulation, there is a lower chance of experiencing gastrointestinal adverse effects while also extending the duration of medication absorption and increasing medicinal efficacy. Enteric coated tablets are solid unit dose forms for oral administration that bypass the stomach and transport the medication straight to the small intestine. Given that the name “enteric” refers to the small intestine, enteric coatings prevent the release of medication before it reaches this organ. A coated surface that is stable at the stomach’s very acidic pH is how most enteric coatings work.

Keywords: Diclofenac Sodium; Tablets; Nonsteroidal Anti-Inflammatory Medication

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