Nanomedicine & Nanotechnology Open Access (NNOA)

ISSN: 2574-187X

Mini Review

Outfitting COVID-19: An Effective Therapeutic Approach

Authors: Patra SK*

DOI: 10.23880/nnoa-16000298


Use of antisense oligonucleotides of the type 3′-(N)x-AAAUUUG-(N)x-5′ against slippery sequence and polynucleotides against pseudoknots forming sequences of SARS-CoV-2 RNA would block the first translation of ORF1a and ORF1b and hence dwindle the virus replication. It is easy to synthesize and deliver the antisense oligonucleotides to the target by directly injecting the nano formulation into the blood.

Keywords: Oligonucleotides; Nanoparticle; Slippery Sequence; Pseudoknots

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