Journal of Infectious Diseases & Travel Medicine (JIDTM)

ISSN: 2640-2653

Review Article

Artificial Intelligence Empowers Global Infectious Disease Prevention and Control: Opportunities and Challenges

Authors: Sijia W and Jue L

DOI: 10.23880/jidtm-16000195

Abstract

Artificial intelligence (AI) has rapidly emerged as a powerful tool in the global effort to prevent and control infectious diseases. With the growing burden of pandemics, antimicrobial resistance (AMR), and travel-related outbreaks, traditional public health responses face significant challenges in speed, scale, and coordination. AI technologies—ranging from machine learning (ML) and natural language processing (NLP) to deep learning and generative models—offer new capabilities across surveillance, early outbreak detection, diagnostics, modeling, vaccine development, public communication, and resource allocation. This review synthesizes the expanding applications of AI in infectious disease prevention and control and highlights its transformative potential in improving preparedness and response. AI enables real-time integration of heterogeneous data sources, supports precision diagnostics in low-resource settings, accelerates vaccine target identification, and enhances public health communication during crises. However, its implementation is not without challenges. These include data quality and bias, privacy and security, technical limitations, transparency and trust, ethical concerns, misinformation, regulatory gaps, cost and infrastructure constraints, and system fragmentation. To maximize AI’s benefits, policy frameworks should promote equitable data access, interdisciplinary collaboration, and inclusive governance mechanisms. Technical development should also prioritize transparency, adaptability, and contextual relevance. AI has the potential to reshape global infectious disease prevention and control, but realizing its promise requires deliberate, coordinated efforts to overcome structural, ethical, and technical barriers.

Keywords: Artificial Intelligence (AI); Infectious Disease Control; Global Health; Disease Surveillance; Ethical Challenges

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