Potential Medicinal Herbs and Secondary Metabolites in Combating Corona Virus

Authors:

DOI: 10.23880/ipcm-16000283

Volume 9, Issue 1

Abstract

COVID-19 first came into the limelight at the end of 2019, causing severe respiratory problems. The genome of the SARSCoV- 2 has several structural and non-structural proteins like papain-like protease (PLpro), 3C-like protease (3CLpro), RNAdependent RNA polymerase (RdRp), helicase, serine protease, and spike protein which are essential for its replications. The main target is to inhibit the activities of these proteins and if we can do this, we may get a remedy for COVID-19. There are several herbal and phytochemical remedies which can fight against these proteins thus resulting in the weakening the COVID-19 infections but till now no confirmed treatment or cure has been established for research purposes. Various plants and their components have been introduced against SARS-CoV-2 whether to find out acting against SARS-CoV-2 or not. There are no such drugs or vaccines which can efficiently act against COVID-19 infections. It has been shown that in In-silico studies, various natural products have a strong binding affinity for the non-structural proteins of the virus. The only function is to minimize the fatal rate. There are several immune boosters which accelerate the immunological functions of humans thus giving the energy to fight against COVID-19. It is expected that these phytochemical constituents may be considered targets for the drug development against SARS-CoV-2.

Keywords: Medicinal Plants; Secondary Metabolites; Coronavirus; SARS-CoV-2; Molecular Mechanisms

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