ISSN: 2476-2490
Authors: Lawson Afouda S¹* , Avakoudjo F² , Adjadohoun S³ , Médji S¹ , Takin R⁴ , Gnangnon F⁵ , Baglo T⁶ and Adjibabi W¹
Introduction: We report a rare case of facial metastasis from a gastrointestinal stromal tumor (GIST). Case report: A 70-year-old patient was admitted to the ENT-HN department of CNHU-HKM in 2018 for a recurring tumor on the right side of his face. His medical history includes right mandible surgery in 2015 and 2017. The pathological examination of the second surgical specimen identified a schwannoma. Postoperatively, a mass appeared at the expense of the parotid gland. A total parotidectomy in 2018 confirmed the same histological type. Two months later, the evolution was marked by the appearance of subcutaneous nodules in line with the surgical scar and in the parotid lodge. The pathological examination, complemented by immunohistochemistry of the extracted nodules in 2019, revealed metastatic lesions with an intestinal origin. The patient was put on Imatinib 100 (GLIVEC® 100) and experienced an improvement in his clinical condition, followed by a gradual deterioration. The search for the primary focus isolated a rectal tumor with neighboring metastatic foci. The patient passed away in 2021. Conclusion: Mandibular and parotid metastases from a gastrointestinal stromal tumor (GIST) are rare. Immunohistochemistry, complementary to pathology, is necessary. Survival is better appreciated when the diagnosis is early, and treatment is based on targeted therapies.
Keywords: Metastases; TSGI; Mandibular Tumor; Parotid Tumor; Imatinib
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