MR Perfusion-Diffusion Mismatch in Acute-Recurrent Ischemic Stroke: Quantitative and Qualitative Progression from Malignant to Misery Profile

Authors: Roldan-Valadez E*, Lopez-Mejia M, Rios-Hoyo A, de la Pena R and Corona-Cedillo R

DOI: 10.23880/crij-16000125

Volume 2, Issue 2

Abstract

We report the use magnetic resonance perfusion to image penumbra, in a patient with acute ischemic stroke as a tool to differentiate candidates for endovascular therapy. A 62-year-old man with three episodes of acute-recurrent ischemic stroke related to infective endocarditis underwent brain MRI on days 1st, 8th and 15th; his perfusion profiles evolve from malignant to misery on days 8th and 15th. Because conventional MRI is relatively insensitive to changes of acute ischemia, it should be supplemented with DWI-PWI sequences to identify patients in the hyperacute-ischemic phase that would benefit from thrombolysis.

Keywords: Brain Ischemia; Diffusion Magnetic Resonance Imaging; Endocarditis; Perfusion Magnetic Resonance Imaging; Stroke

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