Multifunctional Nanotherapeutics for Drug-Resistant Breast Cancer

Authors: Song Lou*

DOI: 10.23880/beba-16000160

Volume 6, Issue 1

Abstract

Tumors are inherently resilient and always develop drug-resistance, leading to poor patient therapy effect. With the developing of sophisticated analytical tools, some novel strategy on improving targeting of anti-cancer delivery is developed to better thwart drug-resistance. This report demonstrates a multilayered nano-system to serve as a multifunctional platform for the treatment of drug-resistant breast cancers. This nano-system is composed of a poly (lactic-co-glycolic acid) core, a liposome second layer, and a hyaluronic acid outmost layer. The different types of drug, loaded in different layers, are released in a controlled and sequential manner upon internalization and localization. This recreated the time-staggering effect necessary for maximal efficacy

Keywords: Drug; Resistant; Breast Cancer

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